Should teenagers be taking all these medications for adhd? I worry about taking something during these developing years. Shouldn't they get help, but talk about the issues and giving problem solving strategies?
We often talk about placebo effects in medicine, but how seriously should psychiatry take the nocebo effect, especially when side effects and long-term dependency are framed in certain ways? If the chemical imbalance narrative was overstated, could it have functioned as a kind of nocebo, reinforcing people’s sense that their brains are defective and biologically broken?
Hello Joanna, what is your opinion on the efficacy of psychedelics in treating neuroses including addictions for opioids and alcohol, and what is the chemical mechanism by which they work in the brain?
Hi Joanna, now that the SSRI house of cards is coming tumbling down, what other medications or interventions do you worry may be due a similar reckoning? And what could be the fallout of this? I suspect statins (granted not your field) due to number needed to treat if nothing else, but what are your thoughts?
Why do uncivilized people living in Nature not display the crippling mental maladies so common among people of techno-industrial society? While abundant among humans living under Progress, depression, anxiety, purposelessness, and despair do not present among people living in Nature, who have the means for survival in the face of what Nature presents.
Kaczynski's notion of The Power Process - in brief, intrinsic fulfillment due to having the ability to survive in Nature - seems an adequate explanation; lacking such survival capability, civilized people exchange obedience for the means of survival, and are subject to so many forces beyond their control in addition to Nature: markets, laws, domestic politics, international agreements, supply chains, hiccups in the technological backbone of society. Like zoo animals, we inhabit a created environs far removed from the natural world we evolved for, where we are then drugged to accept it passively, without anger or disruption to Technology's advancement.
Having just come through a season of mourning in our lives after a difficult season of caretaking, I have questions about our culture pushing people to "be happy," when they have every reason to be sad. Are primary care providers too quick to write prescriptions for SSRIs because patients want to escape sadness or anxiety when the patients should be referred to a counselor?
I've experienced major financial hardship over the past year, and getting in touch with faith and spirituality has helped me personally, a lot. I recently became part of a Lutheran church. God might not always take away suffering, but its in our suffering when he is with us the most, and experiencing our suffering with us ✝️
Re your promotion of Qualia Stem Cell, doesn’t the body regulate DNA of stem cells as needed? Should DNA in our living bodies be messed about with? That’s what mRNA vaccines did as part of the global mass vaccine trial during covid.
I agree. It's more than ironic that in a show about overmedicating depressed people with drugs that don't work, Trig is promoting "stem cell boosting" pharmaceuticals. Not a good look, Trig.
What’s your stance on Jordan Peterson ‘in the middle’ model, which is that some people respond really well to antidepressants and some people don’t, depending on the type of depression they have?
How much is your field being effected by the reproducibility crisis? Are people able to set up studies that give them the result they want, even when dealing with objective data? I remember hearing once that the best science can do is present models that represent reality, and that we should be careful not to confuse those models with reality itself. How far are we from modeling the human brain? Given the implications of AI and transhumanism, would we ever want to?
As someone with a life long form anxiety due to autism, is part of the reason for depression due to learned helplessness? Also is avoiding challenges and stressful situations contribute to higher anxiety because we don't develop the life skills to deal with it?
I think it depends on the person. I've always had issues with avoidant personality symptoms, but have grown enormously from challenging myself, but I've seen it have the opposite effect, DISASTEROUSLY, for other people. The problem is that social situations present us with uncertainty, and it's hard to predict what someone's going to say. For me the anxiety came from knowing how to respond, because a lot of times people bring up things I just don't have any thoughts on. Making myself more quick witted and able to respond to things “on the fly” helped me become less anxious. Social situations are often fluid, and you need to be a good improviser to be able to navigate them gracefully
Unlike the airline industry, there is no central way to report problems or concerns and also without blame. How can the medical profession learn from its mistakes?
To put it bluntly: those who think in a straight forward manner and are honest with themselves and others - however uncomfortable the conclusions they reach - are less susceptible to depression and its possible negative psychiatric consequences than those who constantly kid themselves. Discuss.
Diabetes , High Blood pressure , heart failure are all at a molecular level dysfunctions of bio-chemical reactions . In the same way brain function is a mass of chemical reactions , depression is one unpleasant result of them
Would you reduce the prescription of insulin , blood pressure & heart failure meds and ask people to build up resilience to these conditions ?
Brain neurochemistry is very difficult to study , you cant take a piece of a depressed persons brain and analyse its chemistry. But better drugs will come as they always do , many brain drugs are far better than they were decades ago.
I once cracked a dry humour joke in front of my GP, and the first thing she did was prescribe me an antidepressant. It was said to be a "mild, natural based antidepression". The pamphlet noted it takes two weeks to be fully active and up to five weeks to leave the system. Side effects included literal night tremors, which I personally experienced. Other than the fact that society has deemed any immediately obvious "non-happy" labeled emotion as depression, and the medication starts to affect the brain in such a way long term and when unconscious, how do you think we will be able to, as a society, start making changes to the narrative from the two extremes namely; never having negative emotion, or wearing your depression as a victom and mental illness badge? Will we be able to get back to a time of facing emotions rather than avoiding them, or is this just going to spiral more, considering how quickly and easily the drugs are being prescribed?
Should teenagers be taking all these medications for adhd? I worry about taking something during these developing years. Shouldn't they get help, but talk about the issues and giving problem solving strategies?
We often talk about placebo effects in medicine, but how seriously should psychiatry take the nocebo effect, especially when side effects and long-term dependency are framed in certain ways? If the chemical imbalance narrative was overstated, could it have functioned as a kind of nocebo, reinforcing people’s sense that their brains are defective and biologically broken?
Hello Joanna, what is your opinion on the efficacy of psychedelics in treating neuroses including addictions for opioids and alcohol, and what is the chemical mechanism by which they work in the brain?
Hi Joanna, now that the SSRI house of cards is coming tumbling down, what other medications or interventions do you worry may be due a similar reckoning? And what could be the fallout of this? I suspect statins (granted not your field) due to number needed to treat if nothing else, but what are your thoughts?
Why do uncivilized people living in Nature not display the crippling mental maladies so common among people of techno-industrial society? While abundant among humans living under Progress, depression, anxiety, purposelessness, and despair do not present among people living in Nature, who have the means for survival in the face of what Nature presents.
Kaczynski's notion of The Power Process - in brief, intrinsic fulfillment due to having the ability to survive in Nature - seems an adequate explanation; lacking such survival capability, civilized people exchange obedience for the means of survival, and are subject to so many forces beyond their control in addition to Nature: markets, laws, domestic politics, international agreements, supply chains, hiccups in the technological backbone of society. Like zoo animals, we inhabit a created environs far removed from the natural world we evolved for, where we are then drugged to accept it passively, without anger or disruption to Technology's advancement.
Wow, that is actually a really good question 🤔
Having just come through a season of mourning in our lives after a difficult season of caretaking, I have questions about our culture pushing people to "be happy," when they have every reason to be sad. Are primary care providers too quick to write prescriptions for SSRIs because patients want to escape sadness or anxiety when the patients should be referred to a counselor?
Sorry you had to go through that 🙏
I've experienced major financial hardship over the past year, and getting in touch with faith and spirituality has helped me personally, a lot. I recently became part of a Lutheran church. God might not always take away suffering, but its in our suffering when he is with us the most, and experiencing our suffering with us ✝️
Re your promotion of Qualia Stem Cell, doesn’t the body regulate DNA of stem cells as needed? Should DNA in our living bodies be messed about with? That’s what mRNA vaccines did as part of the global mass vaccine trial during covid.
I agree. It's more than ironic that in a show about overmedicating depressed people with drugs that don't work, Trig is promoting "stem cell boosting" pharmaceuticals. Not a good look, Trig.
What’s your stance on Jordan Peterson ‘in the middle’ model, which is that some people respond really well to antidepressants and some people don’t, depending on the type of depression they have?
How much is your field being effected by the reproducibility crisis? Are people able to set up studies that give them the result they want, even when dealing with objective data? I remember hearing once that the best science can do is present models that represent reality, and that we should be careful not to confuse those models with reality itself. How far are we from modeling the human brain? Given the implications of AI and transhumanism, would we ever want to?
As someone with a life long form anxiety due to autism, is part of the reason for depression due to learned helplessness? Also is avoiding challenges and stressful situations contribute to higher anxiety because we don't develop the life skills to deal with it?
I think it depends on the person. I've always had issues with avoidant personality symptoms, but have grown enormously from challenging myself, but I've seen it have the opposite effect, DISASTEROUSLY, for other people. The problem is that social situations present us with uncertainty, and it's hard to predict what someone's going to say. For me the anxiety came from knowing how to respond, because a lot of times people bring up things I just don't have any thoughts on. Making myself more quick witted and able to respond to things “on the fly” helped me become less anxious. Social situations are often fluid, and you need to be a good improviser to be able to navigate them gracefully
Unlike the airline industry, there is no central way to report problems or concerns and also without blame. How can the medical profession learn from its mistakes?
To put it bluntly: those who think in a straight forward manner and are honest with themselves and others - however uncomfortable the conclusions they reach - are less susceptible to depression and its possible negative psychiatric consequences than those who constantly kid themselves. Discuss.
Diabetes , High Blood pressure , heart failure are all at a molecular level dysfunctions of bio-chemical reactions . In the same way brain function is a mass of chemical reactions , depression is one unpleasant result of them
Would you reduce the prescription of insulin , blood pressure & heart failure meds and ask people to build up resilience to these conditions ?
Brain neurochemistry is very difficult to study , you cant take a piece of a depressed persons brain and analyse its chemistry. But better drugs will come as they always do , many brain drugs are far better than they were decades ago.
I once cracked a dry humour joke in front of my GP, and the first thing she did was prescribe me an antidepressant. It was said to be a "mild, natural based antidepression". The pamphlet noted it takes two weeks to be fully active and up to five weeks to leave the system. Side effects included literal night tremors, which I personally experienced. Other than the fact that society has deemed any immediately obvious "non-happy" labeled emotion as depression, and the medication starts to affect the brain in such a way long term and when unconscious, how do you think we will be able to, as a society, start making changes to the narrative from the two extremes namely; never having negative emotion, or wearing your depression as a victom and mental illness badge? Will we be able to get back to a time of facing emotions rather than avoiding them, or is this just going to spiral more, considering how quickly and easily the drugs are being prescribed?
What do you think of SSRIs as a class of drugs? There seems to be some evidence that they can have the opposite of the intended effect.
What about people with bipolar syndrome? if depressive phase can be treated without medication, manic phase should be treatable without drugs too?